Synthesis of aromatic ketones by a transition metal-catalyzed tandem sequence.
نویسندگان
چکیده
Both simple Ag(I) and Au(I) are effective catalysts for a tandem [3,3]-sigmatropic rearrangement/formal Myers-Saito cyclization of propargyl esters to form aromatic ketones. A mechanism in which the metal catalyzes both of these processes through alkyne activation is proposed. By using this method a wide range of aromatic structures including naphthyl, anthracenyl and indole ketones are available from readily available propargyl esters.
منابع مشابه
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عنوان ژورنال:
- Journal of the American Chemical Society
دوره 128 23 شماره
صفحات -
تاریخ انتشار 2006